Senior Loneliness and Why Companionship Matters. What is senior loneliness? Senior loneliness is a feeling of isolation, disconnection, and exclusion that comes with the aging process. It can result in low self-esteem, distorted thinking, depression and even cause health issues. As people grow older, they are more likely to experience loneliness due to lack of contact with family members, friends, or routine social activity. Approved healthcare provides caregivers for your loved ones.